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ABOUT FOLIC ACID

ABOUT BIRTH DEFECTS

FURTHER READING

 
     
   

REFERENCES AND RESOURCES

References

  1. What is folic acid?
  2. What do women know about folic acid?
  3. What are NTDs and how are they caused?
  4. Who is at risk for an NTD-affected pregnancy?
  5. What is NC's rate of NTDs?
  6. Where can I get patient education materials?
And further


1. What is folic acid?
Centers for Disease Control and Prevention (1992). Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects.
Morbidity and Mortality Weekly Report 41, 1-7.
http://www.cdc.gov/mmwr/preview/mmwrhtml/00019479.htm

Centers for Disease Control and Prevention (1998). Preventing Neural Tube Birth Defects:
a Prevention Model and Resource Guide. US DHHS.

Elkin, A.C., & Higham, J. (2000). Folic acid supplements are more effective than increased dietary folate intake in elevating serum folate levels.
BJOG 102(2), 285-9.

Institute of Medicine, Food and Nutrition Board (1999).
Dietary reference intakes: thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington, DC: National Academy Press.

Milunsky, A., Jick, H., Jick, S.S., et al. (1989). Multivitamin/folic acid supplement in early pregnancy reduces the prevalence of neural tube defects.
JAMA 262, 2847-52.

Mulinare, J., Cordeo, J.F., Erickson, J.D., et. al. (1988). Periconceptional use of multivitamins and the occurrence of neural tube defects.
JAMA 260, 3141-45.

Watikins, M.L. (1998). Efficacy of folic acid prophylaxis for the prevention of neural tube defects.
MRDD Research Reviews 4, 282-290.

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2. What do women know about folic acid?
Center for Disease Control and Prevention (2001). Are women with recent live births aware of the benefits of folic acid?
Morbidity and Mortality Weekly Report 50(06), 1-14.
http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5006a1.htm

Meyer, R.E., Hayes, A., Morgan, A., et al. (publication pending).
Knowledge and use of folic acid among North Carolina Women. NC State Center for Health Statistics.

March of Dimes (2000).
Folic Acid and the Prevention of Birth Defects: A national survey of pre-pregnancy awareness and behavior among women of childbearing age 1995-2000.

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3. What are NTDs and how are they caused?
Little, J., & Elwood, J.M. (1991). Epidemiology of neural tube defects. In M. Kiely (Ed.),
Reproductive and perinatal epidemiology (pp. 251-336). Boca Raton: CRC Press.

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4. Who is at risk for an NTD-affected pregnancy?
Hernadez-Diaz, S., Werler, M.M., Walker, A.M., et al. (2000) Folic acid antagonists during pregnancy and the risk of birth defects.
NEJM 343, 1608-14.

Little, J., & Elwood, J.M. (1991). Epidemiology of neural tube defects. In M. Kiely (Ed.),
Reproductive and perinatal epidemiology (pp. 251-336). Boca Raton:CRC Press.

Shaw, G.M., Velie, E.M., & Schaffer, D. (1996). Risk of neural tube defect-affected pregnancies among obese women.
JAMA 275, 1093-1096.

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5. What is NC's rate of NTDs?
Centers for Disease Control and Prevention (1999). Folate Status in Women of Childbearing Age --- United States.
Morbidity and Mortality Weekly Report 1999 49(42), 962. http://www.cdc.gov/mmwr/PDF/wk/mm4942.pdf

Elwood, J.M., Little, J., & Elwood, J.H. (1992). Epidemiology and Control of Neural Tube Defects. Oxford:Oxford Univeristy Press.

Morgan, A., Randolph, L, Meyer, R., Powers, K., & Verbiest, S. (2000).
North Carolina Birth Defects Monitoring Program Surveillance Report. NC Division of Public Health.

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6. Where can I get patient education materials?

Web Resources:

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